OpenAI Agent Skills

Submit compact AlphaFold Protein Structure Database API requests for prediction, UniProt summary, sequence summary, and annotation lookups.

Submit compact Bgee SPARQL requests for healthy wild-type expression metadata and ontology-aware lookup patterns.

Submit compact BindingDB REST API requests for ligand-target binding lookups by PDB, UniProt, or similarity search.

Fetch compact BioBank Japan PheWAS summaries for single variants by accepting rsID, GRCh38, or GRCh37 input and resolving to the required GRCh37 query.

Submit compact bioRxiv and medRxiv API requests for details, publication-linkage, and DOI lookups.

Submit compact BioStudies and ArrayExpress API requests for free-text search and accession-based study retrieval.

Submit compact cBioPortal API requests for studies, molecular profiles, mutations, clinical data, and samples.

Submit compact CELLxGENE Discover API requests for public collection and dataset metadata.

Submit compact ChEBI 2.0 API requests for chemical search, compound lookup, ontology traversal, and structure metadata.

Submit compact ChEMBL API requests for activity, molecule, target, mechanism, and text-search endpoints.

Submit compact CIViC GraphQL requests for cancer variant interpretation schema inspection and targeted evidence retrieval.

Submit compact ClinicalTrials.gov API v2 requests for study search, metadata, enums, search areas, and field statistics.

Submit compact ClinVar Clinical Tables and NCBI Variation requests for search, VCV, RCV, SCV, and RefSNP lookups.

Submit compact EFO OLS4 requests for search, term lookup, children, and descendants.

Submit compact ENCODE REST API requests for object lookups, portal-style search, and metadata retrieval.

Submit compact Ensembl REST API requests for lookup, overlap, cross-reference, and variation endpoints.

Submit compact EpiGraphDB API requests for ontology, literature, MR, gene-drug, and support-path evidence.

Submit compact eQTL Catalogue API requests for association retrieval and documented metadata endpoints.

Submit compact EVA REST requests for species metadata and archived variant lookups.

Fetch compact FinnGen PheWAS summaries for single variants by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query.

Submit compact Genebass gene burden requests for one Ensembl gene ID and one burden set.

Submit compact gnomAD GraphQL requests for frequency, gene constraint, and variant context queries.

Fetch GTEx single-tissue eQTL associations from one variant input by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query for the GTEx v2…

Submit compact GWAS Catalog REST API v2 requests for studies, associations, SNPs, EFO traits, genes, publications, loci, and metadata.

Submit compact HMDB search requests for metabolites, proteins, diseases, and pathways.

Submit compact Human Protein Atlas requests for gene JSON, search downloads, and page-level tissue or cell-line lookups.

Submit compact IPD REST requests for HLA allele and cell-level metadata using the public IPD query API.

Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO -> GWAS -> coordinates -> Open Targets L2G/coloc -> eQTL -> burden/coding context),…

Submit compact MetaboLights requests for study discovery and study-level metabolomics metadata.

Submit compact MGnify API requests for microbiome studies, samples, and biome metadata.

Submit, poll, and summarize NCBI BLAST Common URL API jobs (Blast.cgi) for nucleotide or protein sequences.

Submit compact Clinical Tables NCBI Gene requests for human gene lookup, pagination, and field selection.

Submit compact NCBI Datasets v2 requests for assembly, genome, taxonomy, and related metadata endpoints.

Submit compact NCBI Entrez E-Utilities requests for PubMed, Gene, Protein, Nucleotide, PMC metadata, and GEO metadata workflows.

Submit compact NCBI PMC Open Access requests for article/file availability metadata.

Submit compact Open Targets Platform GraphQL requests for target, disease, drug, variant, study, and search data, including associated-disease datasource heatmap…

Submit compact PharmGKB API requests for genes, variants, clinical annotations, dosing guidelines, and search.

Submit compact PRIDE Archive API requests for proteomics project discovery and project-level metadata.

Submit compact ProteomeXchange PROXI requests for datasets, libraries, peptidoforms, proteins, PSMs, spectra, and USI examples.

Submit compact PubChem PUG REST requests for compound properties, descriptions, assay summaries, and substance metadata.

Submit compact QuickGO requests for GO terms, annotations, and ontology traversal.

Submit compact RCSB PDB requests for core metadata, Search API queries, and FASTA downloads.

Submit compact Reactome ContentService requests for pathway, event, participant, search, and diagram-related data.

Route broad or ambiguous life-sciences research requests to the right skills, normalize core entities, optionally parallelize independent evidence gathering with…

Submit compact Rhea reaction search requests for biochemical reactions and reaction IDs.

Submit compact RNAcentral API requests for RNA entry browsing, single-entry lookup, and cross-reference retrieval.

Submit compact STRING API requests for network, interaction partner, and enrichment endpoints.

Fetch compact TPMI PheWAS summaries for single variants by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query.

Fetch compact UKB-TOPMed PheWAS summaries for single variants by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query.

Submit compact UniProt REST API requests for UniProtKB, UniRef, UniParc, and FASTA stream endpoints.

Use when building public-equity-investing catalyst calendars.

Use when creating source-backed public issuer tearsheets.

Produce Public Equity Investing comparable-company valuation in report or workbook mode.

Use when building public-equity DCF valuation workbooks.

Use when running first-pass QC on Public Equity Investing decks or reports.

Use when analyzing public-company earnings after results, guidance, transcript, or call commentary.

Use when preparing full pre-earnings preview reports with executive summary, expectation bar, guidance credibility, KPI dashboard, scenarios, and call questions.

Use when translating a specific event, policy change, macro shock, or industry development into public-equity issuer, sector, earnings, valuation, positioning, and…

Safely update public-company Excel model copies from source-to-model maps; emits XLSX as the hero artifact and CSV/log/manifest as support.

Use when analyzing dated public-equity event paths, probabilities, payoffs, and expected returns.

Use when normalizing public-company financials from source materials.

Use when triaging public-equity idea candidates.

Use when building public-equity-investing initiating coverage reports.

Use when building PM-facing Public Equity Investing trade pitches, including sparse-context or partial-section requests.

Use when creating Public Equity Investing meeting prep briefs.

Use when drafting or reviewing formal public-equity investment memos.

Use when auditing existing Public Equity Investing models or spreadsheets.

Use when sizing Public Equity Investing positions, finding equity hedges, or building an integrated position-and-hedge risk plan from a listed-equity thesis.

Route Public Equity Investing workflows for listed-company and public-security research, earnings analysis, valuation, model updates, long/short pitches, catalysts,…

Use when turning a public-equity base case, model, thesis, event, or catalyst into scenario skew, sensitivity, breakpoint, and PM action-threshold analysis.

Use when building or updating Public Equity Investing thesis trackers.

Use when building public-equity three-statement operating model workbooks.

Initialize, inspect, save, update, forget, export, or explicitly reset the Public Equity Investing plugin's local user context, source setup, or optional automation…

Make data visualizations accessible and inclusive.

Render data visualizations with Canvas2D.

Build custom data visualizations with D3.

Design dashboards and live visualization systems.

Route web data visualization work.

Design, critique, route, and implement Gantt charts and schedule visualizations.

Design geospatial and cartographic visualizations.

Build data visualizations with declarative grammars.

Choose and apply automatic layout strategies for node-link diagrams and connected-node visuals.

Integrate data visualizations into React and Next.js applications.

Lay out and export data-rich reports and documents.

Design and implement parallax scrolling and scrollytelling data visualizations.

Design statistically honest and uncertainty-aware visualizations.

Test data visualizations and dashboards.

Render WebGL-accelerated data visualizations with Three.js, raw WebGL, deck.gl, luma.gl, PixiJS, Sigma.js, Plotly WebGL traces, ECharts GL, CesiumJS, Babylon.js, or…

Build typed data visualizations in TypeScript.

Design, critique, read, write, render, and implement UML and UML-like software diagrams.

Choose, lay out, critique, and explain data visualizations.

Kick off public 16S, 18S, ITS, COI, or other marker-gene amplicon microbiome workflows using nf-core/ampliseq, QIIME2, DADA2, and Cutadapt.

Route BCL, FASTQ, BAM/CRAM, count-matrix, or VCF sequencing requests to the right public NGS analysis skill and ask only the missing assay-specific setup questions.

Run or plan ATAC-seq QC, alignment, TSS enrichment, fragment-size, blacklist, peak-calling, consensus peak, and differential accessibility workflows.

Validate Illumina BCL run folders and sample sheets, plan demultiplexing, review index/UMI/lane choices, run BCL-to-FASTQ conversion, and interpret demux metrics while…

Dispatch bulk RNA-seq requests to FASTQ-to-count QC or count-matrix differential-expression skills using nf-core/rnaseq, STAR, Salmon, featureCounts, MultiQC, and…

Run or plan bulk RNA-seq FASTQ-to-count processing with sample-sheet, strandedness, genome annotation, alignment or pseudoalignment, MultiQC, and count-matrix QC checks.

Run or plan bulk RNA-seq differential-expression analysis from count matrices with replicate, design formula, contrast, batch, normalization, QC plot, and result-table…

Run or plan ChIP-seq, CUT&RUN, or CUT&Tag QC, control handling, spike-in, peak calling, broad-vs-narrow target selection, replicate, bigWig, and differential binding…

Run or plan deep germline WGS, WES, targeted-panel, cohort, or trio variant-calling workflows with reference-build, known-sites, QC, joint-calling, and annotation checks.

Run or plan tumor-normal, tumor-only, WGS, WES, or cancer-panel somatic variant workflows with pairing, contamination, panel-of-normals, purity, QC, and annotation…

Run or plan targeted DNA panel variant workflows that use UMIs, duplex consensus reads, molecular barcodes, low-frequency calling, target coverage, and panel-specific QC.

Dispatch WGS, WES, or targeted DNA variant requests to germline, somatic, or UMI-panel skills, then plan public nf-core/sarek, GATK4, DeepVariant, samtools, or bcftools…

Dispatch ATAC-seq, ChIP-seq, CUT&RUN, or CUT&Tag requests to assay-specific QC, alignment, signal-track, peak-calling, consensus, and differential peak workflows.

Validate FASTQ inputs, run local FastQC/MultiQC QC, interpret QC signals, and optionally execute fastp or Cutadapt trimming branches without overwriting raw reads.

Check whether public NGS tools and packages already exist before downloading, installing, or running a sequencing pipeline.

Route single-cell or single-nucleus RNA-seq FASTQs to public count-generation workflows and defer post-count matrix QC, annotation, clustering, and UMAP analysis to the…

Kick off public shotgun metagenomics QC, host-depletion, taxonomic profiling, and functional profiling workflows using nf-core/taxprofiler, Kraken2, Bracken, MetaPhlAn,…

Process, quality-control, annotate, and visualize single-cell or single-nucleus RNA-seq datasets across tissues and species.

Assess an immutable patch artifact's program impact, regression risk, and auto-merge eligibility.

Use when Codex is already in the attack-path-analysis phase of a security scan or the user explicitly asks to trace a security finding from source to sink and calibrate…

Use when the user asks for a deep, exhaustive, multi-pass, or variance-reducing repository-wide or scoped-path Codex Security scan.

Define, review, or update SECURITY.md guidance for a repository or component.

Use when Codex is already in the finding-discovery phase of a security scan or the user explicitly asks to discover candidate security findings in a repository or code…

Use when the user explicitly asks to fix and verify a validated or plausible security finding.

Develop evidence-backed structural and architectural security hardening proposals from vulnerability disclosures, supplied findings, incident or assessment documents,…

Review a pull request, commit, branch diff, or working-tree patch for security vulnerabilities.

Use for a standard, single-pass security audit of an entire repository or a scoped path, package, folder, or submodule with no diff to review.

Use when Codex is already in the threat-modeling phase of a security scan, the user explicitly invokes $threat-model, or the user explicitly asks to create, update, or…

Track validated Codex Security findings in Linear, Jira, GitHub issues, or draft GitHub security advisories.

Use when the user supplies or imports existing security findings, vulnerability reports, or security/vulnerability Jira/Linear tickets from scanners, advisories, GitHub,…

Use when Codex is already in the validation phase of a security scan or the user explicitly asks to determine whether one or more candidate security findings are valid.

Use only when the user explicitly requests verification that a security fix remediates a reported vulnerability.

Turn vulnerability notes, disclosure reports, PoCs, source code, or Codex Security findings into self-contained, sceptically validated, natural-sounding vulnerability…

Assess whether structured data, query results, dashboards, or analytical evidence are trustworthy enough to use.

Build source-backed dashboards for monitoring performance, exploring drivers, or acting on product and business metrics.

Build polished analytical reports for executive, product, business, or technical audiences.

Create, update, inspect, or repair Data Analytics semantic layers.

Design KPI frameworks, metric definitions, targets, guardrails, and measurement plans for product or business decisions.

Gather business context from connected or provided sources so downstream analysis starts with the right framing.

Route Data Analytics plugin-level requests and broad analytics work to the right focused workflow.

Create, edit, or validate reproducible SQL or Python notebooks.

Prepare KPI readouts, scorecards, WBR/MBR/QBR updates, and executive summaries from quantitative business or product metrics; use when the task is to report status,…

Estimate market, segment, or opportunity size with transparent assumptions and uncertainty.

Diagnose why a metric changed or differs from expectation.

Analyze product or business data to support a decision or recommendation.

Publish a validated Data Analytics report or dashboard artifact through Sites.

Validate whether an analysis is accurate, well-supported, and ready to share or use for a decision.

Design, build, revise, or QA quantitative charts and figures.

Bridge macOS SwiftUI into AppKit narrowly.

Build, run, and debug macOS apps with shell-first Xcode and Swift workflows.

Implement and review macOS SwiftUI Liquid Glass UI.

Prepare macOS packaging and notarization workflows.

Inspect macOS signing, entitlements, and Gatekeeper issues.

Build, run, and test SwiftPM macOS packages and executables.

Build macOS SwiftUI scenes and components with desktop patterns.

Add and verify lightweight macOS runtime telemetry.

Triage macOS tests across Xcode and SwiftPM.

Refactor macOS SwiftUI views and scenes into stable structure.

Customize macOS SwiftUI windows and scene behavior.

Audit or critique a product flow, journey, workflow, funnel, onboarding path, checkout path, settings path, screen, or multi-step product experience by capturing…

Internal prototype QA helper.

Mandatory design-brief gate for clarifying the product and outcome.

Generate image-based alternatives, remixes, or new design directions from a Product Design brief.

Implement a selected image, screenshot, mockup, or Image Gen reference as a faithful, responsive frontend.

Use when Product Design is explicitly invoked, or when the user's main goal is to explore a design, research UX, audit or critique a flow, faithfully clone a visual…

Run fast, source-grounded UX research on the highest-signal problems users are experiencing with a user-specified digital product.

Share a runnable prototype using the user's preferred deployment tool.

Clone a live URL as a runnable frontend-only local app.

Load or manage Product Design's saved user context.

Design App Intents, app entities, and App Shortcuts for iOS system surfaces.

Build, run, and debug iOS apps on Simulator with XcodeBuildMCP.

Capture and interpret iOS Simulator ETTrace profiles.

Capture and inspect iOS leaks and memgraphs.

Mirror an iOS Simulator into the Codex in-app browser and render SwiftUI previews from importable Swift packages in that simulator with hot reload.

Implement and review iOS 26+ SwiftUI Liquid Glass UI.

Audit SwiftUI runtime performance from code first.

Build and refactor SwiftUI UI with component patterns and examples.

Refactor SwiftUI view files into stable, testable structure.

Run browser-game playtests and frontend QA.

Route early browser-game work.

Design UI surfaces for browser games.

Implement 2D browser games with Phaser.

Build React-hosted 3D browser games with React Three Fiber.

Generate and normalize 2D sprite animations.

Implement browser-game runtimes with plain Three.js.

Prepare and optimize browser-game 3D assets.

Set browser-game architecture before implementation.

Use for new frontend applications, dashboards, games, creative websites, hero sections, and visually driven UI from scratch, or when the user explicitly asks for a…

Use when testing, debugging, or making targeted improvements to rendered frontend apps through the Build Web Apps or web dev plugin: local dev servers, UI regressions,…

React and Next.js performance optimization guidelines from Vercel Engineering.

Based on Vercel's React Best Practices →

Manages shadcn components and projects — adding, searching, fixing, debugging, styling, and composing UI.

Guides Stripe integration decisions — API selection (Checkout Sessions vs PaymentIntents), Connect platform setup (Accounts v2, controller properties),…

Based on Stripe's Stripe Best Practices →

Postgres performance optimization and best practices from Supabase.

Based on Supabase's Supabase Postgres Best Practices →

Prompt- and template-complete Google Docs creation and editing with explicit-instruction-authoritative structural preservation, including semantic roles, relationships,…

Use connected Google Drive as the single entrypoint for Drive, Docs, Sheets, and Slides work.

Write, reply to, and resolve Google Drive comments on Docs, Sheets, Slides, and Drive files with evidence-backed location context.

Analyze and edit connected Google Sheets with range precision.

Route Google Slides authoring requests and derive a design system from a native template or reference deck.

Build, run, deploy, and evaluate OpenAI Agents SDK apps from Codex.

Build, scaffold, refactor, and troubleshoot ChatGPT Apps SDK applications that combine an MCP server and widget UI.

Inspect a ChatGPT Apps MCP server codebase and generate chatgpt-app-submission.json with app info suggestions, tool hint justifications, test cases, and negative test…

Use when an OpenAI API request fails and Codex needs to classify the likely cause, explain the next step, and route to the right follow-up.

Use when Codex is asked to build, run, test, debug, or configure an OpenAI-backed or provider-unspecified AI app, UI, script, CLI, generator, or tool, especially…

Evaluate a local Codex plugin in engineer-friendly language.

Evaluate a local Codex skill in engineer-friendly terms.

Turn plugin-eval findings into a concrete rewrite brief for a Codex skill.

Design custom metric packs for plugin-eval so teams can add local evaluation rubrics that emit schema-compatible checks and metrics.

Help engineers evaluate a local skill or plugin, explain why it scored that way, show what to fix first, measure real token usage, benchmark starter scenarios, or decide…

Use when Creative Production is explicitly invoked or mentioned without a concrete request, when the user asks what Creative Production can do, or when the user wants…

Use when the user wants to create, explore, adapt, refine, polish, or review visual creative such as campaigns, ads, social posts, product imagery, scenes, offers,…

Use when validating Android feature flows in an emulator with adb-driven launch, input, UI-tree inspection, screenshots, and logcat capture.

Gather and interpret Android performance evidence on an adb target using Simpleperf CPU profiles, Perfetto or Compose traces, gfxinfo frame data, dumpsys meminfo…

Guide Codex through instrumenting or extending repositories with OpenAI Ads Measurement Pixel and optional Conversions API (CAPI).

Use when the user asks to inspect Sentry issues or events, summarize recent production errors, or pull basic Sentry health data via the Sentry API; perform read-only…

Use Zotero Desktop from Codex to enable/probe the local API, search a local Zotero library, list items/collections/tags, export BibTeX, insert citation keys into LaTeX…

Generate or edit raster images when the task benefits from AI-created bitmap visuals such as photos, illustrations, textures, sprites, mockups, or transparent-background…

Create and scaffold plugin directories for Codex with a required .codex-plugin/plugin.json, optional plugin folders/files, and baseline placeholders you can edit before…

Guide for creating effective skills.

Install Codex skills into $CODEX_HOME/skills from a curated list or a GitHub repo path.

Build, review, refactor, or architect ASP.NET Core web applications using current official guidance for .NET web development.

Build, scaffold, refactor, and troubleshoot ChatGPT Apps SDK applications that combine an MCP server and widget UI.

Build a composable CLI for Codex from API docs, an OpenAPI spec, existing curl examples, an SDK, a web app, an admin tool, or a local script.

Deploy applications and infrastructure to Cloudflare using Workers, Pages, and related platform services.

Help the user define a concrete, measurable goal before starting work, especially when they ask to use the goal tool, create a goal, set an objective, clarify success…

Use the Figma MCP server to fetch design context, screenshots, variables, and assets from Figma, and to translate Figma nodes into production code.

Connects Figma design components to code components using Code Connect mapping tools.

Generates custom design system rules for the user's codebase.

Translates Figma designs into production-ready application code with 1:1 visual fidelity.

Help address review/issue comments on the open GitHub PR for the current branch using gh CLI; verify gh auth first and prompt the user to authenticate if not logged in.

Use when a user asks to debug or fix failing GitHub PR checks that run in GitHub Actions; use gh to inspect checks and logs, summarize failure context, draft a fix plan,…

Create, repair, validate, visually QA, and package Codex-compatible animated pets and pet spritesheets from character art, generated images, company or prospect brand…

Use when the user asks to create, scaffold, or edit Jupyter notebooks (.ipynb) for experiments, explorations, or tutorials; prefer the bundled templates and run the…

Manage issues, projects & team workflows in Linear.

Migrate supported instruction files, skills, agents, and MCP config into Codex project and global files.

Deploy web projects to Netlify using the Netlify CLI (npx netlify).

Use when the user asks how to build with OpenAI products or APIs, asks about Codex itself or choosing Codex surfaces, needs up-to-date official documentation with…

Use when tasks involve reading, creating, or reviewing PDF files where rendering and layout matter; prefer visual checks by rendering pages (Poppler) and use Python…

Use when the task requires automating a real browser from the terminal (navigation, form filling, snapshots, screenshots, data extraction, UI-flow debugging) via…

Persistent browser and Electron interaction through js_repl for fast iterative UI debugging.

Deploy applications to Render by analyzing codebases, generating render.yaml Blueprints, and providing Dashboard deeplinks.

Use when the user explicitly asks for a desktop or system screenshot (full screen, specific app or window, or a pixel region), or when tool-specific capture capabilities…

Perform language and framework specific security best-practice reviews and suggest improvements.

Analyze git repositories to build a security ownership topology (people-to-file), compute bus factor and sensitive-code ownership, and export CSV/JSON for graph…

Repository-grounded threat modeling that enumerates trust boundaries, assets, attacker capabilities, abuse paths, and mitigations, and writes a concise Markdown threat…

Use when the user asks for text-to-speech narration or voiceover, accessibility reads, audio prompts, or batch speech generation via the OpenAI Audio API; run the…

Transcribe audio files to text with optional diarization and known-speaker hints.

Deploy applications and websites to Vercel.

Based on Vercel's Deploy To Vercel →

Bootstrap, develop, and design modern WinUI 3 desktop applications with C# and the Windows App SDK using official Microsoft guidance, WinUI Gallery patterns, Windows App…

Use only when the user explicitly asks to stage, commit, push, and open a GitHub pull request in one flow using the GitHub CLI (gh).